Real-World Utilization of Carfilzomib (Once or Twice Weekly) Initiated in Patients After a First Relapse Between 2017 and 2022 in France: An Analysis From a Large-Scale Epidemiology of Multiple MYeloma (EmmY) Cohort
This real-world study confirms carfilzomib effectiveness at both dosing frequencies. K triplets resulted in long survivals and Kd remained satisfactory to treat heavily pretreated patients.
Authors
- Karim Belhadj Merzoug
- Olivier Decaux
- Ronan Garlantézec (ORCID: https://orcid.org/0000-0001-7420-6341)
- Lionel Karlin (ORCID: https://orcid.org/0000-0002-1185-4488)
- Claire Calmettes
- Riad Benramdane
- Arthur Bobin (ORCID: https://orcid.org/0000-0002-8416-391X)
- Hakima Mechiche
- Gaëlle Désaméricq (ORCID: https://orcid.org/0000-0003-4636-7361)
- Margaret Macro (ORCID: https://orcid.org/0000-0002-0460-0658)
- Laure Vincent (ORCID: https://orcid.org/0000-0001-5904-1286)
- Thomas Chalopin (ORCID: https://orcid.org/0000-0002-9833-3115)
- Bruno Royer (ORCID: https://orcid.org/0000-0002-8649-7008)
- Aurore Perrot (ORCID: https://orcid.org/0000-0003-0131-8689)
- Cyrille Hulin (ORCID: https://orcid.org/0000-0002-3749-5161)
- Laurent Frenzel (ORCID: https://orcid.org/0000-0002-6085-2163)
- Mohamad Mohty (ORCID: https://orcid.org/0000-0001-8536-7781)
- Mammoun Dib
- Denis Caillot
- Frédérique Orsini Piocell
Institutions
- Université de Tours (FR)
- Université Paris-Est Créteil (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- Université Rennes 2 (FR)
- Université de Poitiers (FR)
- Sorbonne Université (FR)
- Hospital for Sick Children Pediatric Center (US)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Centre Hospitalier Universitaire de Tours (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Institut universitaire du cancer de Toulouse Oncopole (FR)
- Hôpital Lyon Sud (FR)
- Centre Hospitalier Annecy Genevois (FR)
- Centre de Recherche Saint-Antoine (FR)
- Maison des Sciences sociales et des Humanités de Dijon (FR)
- Hôpital Saint-Louis (FR)
- Centre Hospitalier René-Dubos (FR)
- Lymphoma Study Association (FR)
- Lux Research (United States) (US)
- Université d'Angers (FR)
- Université de Rennes (FR)
- Chiesi (France) (FR)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- Clinical Lymphoma Myeloma & Leukemia
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1016/j.clml.2025.08.002
- Citations
- 1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Amgen