Stability of microRNAs in serum and plasma reveal promise as a circulating biomarker
These data demonstrate remarkable stability of miRNAs over time, which should withstand variability in handling and processing that can occur with routine clinical lab draws. Considering the large diversity of miRNAs, this analyte class should be thoroughly investigated as a non-invasive biomarker of diverse disease states.
Authors
- Mehrdad Zarei
- Alexander W. Loftus (ORCID: https://orcid.org/0000-0002-6421-7896)
- Eric Londin (ORCID: https://orcid.org/0000-0003-4331-6366)
- Jonathan J. Hue (ORCID: https://orcid.org/0000-0002-1608-8874)
- Luke Daniel Rothermel (ORCID: https://orcid.org/0000-0001-5700-8028)
- Jordan M. Winter (ORCID: https://orcid.org/0000-0002-5200-6557)
- Erryk Katayama (ORCID: https://orcid.org/0000-0002-2206-8124)
- Hallie J. Graor (ORCID: https://orcid.org/0000-0002-4370-8688)
- Semmer A. Ali
Institutions
- Thomas Jefferson University (US)
- University Hospitals of Cleveland (US)
- The Ohio State University (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Non-coding RNA Research
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1016/j.ncrna.2025.08.001
- Citations
- 7
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 6.55