Electroacupuncture enhances mesenchymal stem cell therapy via improved perfusion and inflammation modulation in peripheral nerve injury: an IVIM-MRI study in rats
EA is more effective than BMSCs alone in promoting nerve repair, enhancing blood flow, and reducing inflammation. Moreover, EA enhances the anti-inflammatory effects of BMSCs. The perfusion fraction (f) is a sensitive biomarker for evaluating nerve repair and perfusion restoration.
Authors
- Jintong Pan (ORCID: https://orcid.org/0009-0009-5959-1590)
- Haodong Qin (ORCID: https://orcid.org/0009-0004-1659-0233)
- Qiuyi Chen (ORCID: https://orcid.org/0009-0009-4792-5266)
- Fanqi Meng (ORCID: https://orcid.org/0000-0002-5238-3459)
- Yueyao Chen (ORCID: https://orcid.org/0000-0002-6225-3359)
- Xuewen Yu (ORCID: https://orcid.org/0000-0003-4774-7139)
- Peiyin Luo
- Wen‐Sheng Huang (ORCID: https://orcid.org/0009-0001-1194-212X)
- Junfeng Li
- Yingying Liang
- Xiao-Feng Lin
- Ruirui Qi
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Siemens (China) (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.3389/fneur.2025.1642150
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38