Oral Health Related Quality of Life and Xerostomia in Cardiovascular Patients

Background: Cardiovascular patients frequently suffer from xerostomia and several modalities has been tried to alleviate the symptom. Improving Oral Health Related Quality of Life (OHRQoL) is a subjective index and considered as the final achievement in oral treatments. The aim of the present study was to evaluate OHRQoL in these patients, as well as its relation to xerostomia and some other factors. Materials and Methods: In this cross-sectional study, 244 patients participated. OHRQoL was assessed by Oral Health Impact Profile 14 (OHIP-14). Xerostomia severity was quantified by the Xerostomia Inventory (XI). Consumed anti-hypertensive drugs, age and gender were also recorded. Data were analyzed using SPSS 22 (IBMversion 22.0, Chicago, USA) and statistical significance level was considered P<0.05. Results: The mean age of participants was score of OHIP-14 was 58.90 ± 5.66 years, of whom 53% were male and 47% female. The mean total OHIP-14 score was 13.33 ± 11.11. Patients with xerostomia consisted 78% of the sample, with a mean XI score of 23.9 ± 5.1. Total and all domain scores of OHIP-14 were directly and significantly correlated with XI score (P<0.001). Also, age had a direct and significant correlation with both OHIP-14 (P<0.001) and XI (P=0.001) scores. Use of cardiovascular drugs was not significantly related to xerostomia presence or severity (P>0.05). Conclusion: The majority of cardiovascular patients suffer from moderate xerostomia, regardless to the type of medication they consume. Xerostomia affects OHRQoL in these patients and should be treated properly to improve their life quality, especially among the elderly.

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Publication Details

Journal
Galen Medical Journal
Published
2025-08-08
DOI
https://doi.org/10.31661/gmj.vi.3805
Primary Topic
Salivary Gland Disorders and Functions
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article
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article

Oral Health Related Quality of Life and Xerostomia in Cardiovascular Patients

Omid Fakheran, Adel Tabesh, Nastaran Shahriari, Hadi Karimzadeh
Galen Medical Journal
Salivary Gland Disorders and Functions
article

Oral Health Related Quality of Life and Xerostomia in Cardiovascular Patients

Omid Fakheran, Adel Tabesh, Nastaran Shahriari, Hadi Karimzadeh
article en

Abstract

Background: Cardiovascular patients frequently suffer from xerostomia and several modalities has been tried to alleviate the symptom. Improving Oral Health Related Quality of Life (OHRQoL) is a subjective index and considered as the final achievement in oral treatments. The aim of the present study was to evaluate OHRQoL in these patients, as well as its relation to xerostomia and some other factors. Materials and Methods: In this cross-sectional study, 244 patients participated. OHRQoL was assessed by Oral Health Impact Profile 14 (OHIP-14). Xerostomia severity was quantified by the Xerostomia Inventory (XI). Consumed anti-hypertensive drugs, age and gender were also recorded. Data were analyzed using SPSS 22 (IBMversion 22.0, Chicago, USA) and statistical significance level was considered P<0.05. Results: The mean age of participants was score of OHIP-14 was 58.90 ± 5.66 years, of whom 53% were male and 47% female. The mean total OHIP-14 score was 13.33 ± 11.11. Patients with xerostomia consisted 78% of the sample, with a mean XI score of 23.9 ± 5.1. Total and all domain scores of OHIP-14 were directly and significantly correlated with XI score (P<0.001). Also, age had a direct and significant correlation with both OHIP-14 (P<0.001) and XI (P=0.001) scores. Use of cardiovascular drugs was not significantly related to xerostomia presence or severity (P>0.05). Conclusion: The majority of cardiovascular patients suffer from moderate xerostomia, regardless to the type of medication they consume. Xerostomia affects OHRQoL in these patients and should be treated properly to improve their life quality, especially among the elderly.

Galen Medical Journal
Isfahan University of Medical Sciences (IR), Medical University of Graz (AT)
Good health and well-being
Openalex Percentile: Top 73%
Salivary Gland Disorders and Functions
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Oral Health Related Quality of Life and Xerostomia in Cardiovascular Patients — Omid Fakheran, Adel Tabesh, et al. · Galen Medical Journal (2025) | TGRS Research Map | TGRS