Screening of an medicinal plant Crinum asiaticum L. bulb extracts for their proximate composition, phytochemical analysis and antioxidant activity

Crinum asiaticum, a traditional medicinal plant has been used for various therapeutic purposes. Therefore, the present study aims to investigate the proximate composition, phytochemical analysis and antioxidant activities of C. asiaticum bulb extracts. C. asiaticum bulb were collected from three different district of Thanjavur, Nagappattinam, Namakkal and analyzed for proximate composition and phytochemical analysis. The results showed that C. asiaticum bulb extracts contained various bioactive compounds including alkaloids, glycosides, flavonoids and phenolic acids. KGVA extracts (KGVA 1, KGVA 2 and KGVA 3) were evaluated for antioxidant activity using H2O2, reducing power and DPPH assay. KGVA 1 and KGVA 2 showed significant antioxidant activity, comparable to ascorbic acid and Vitamin C. KGVA 1 had the highest activity in the DPPH assay. The extracts also contained various polyphenolic compounds including neochlorogenic acid, protocatechuic acid and vanillic acid. This study demonstrates the potential of C. asiaticum bulb extracts as a rich source of bioactive compounds. The results suggested that C. asiaticum may be a valuable plant for the development of new therapeutic agents particularly for the treatment of breast cancer and microbial infections.