Phytochemical, GC-MS analysis and antibacterial activity of leaf extract of Solanum trilobatum l.

The study objective was to use GC-MS analysis to extract the phytochemical components from Solanum trilobatum leaves. For phytochemical investigation, S. trilobatum leaves were evaluated for possible antibacterial action against Bacillus subtilis and Staphylococcus aureus. The ethanolic leaf extract of S. trilobatum included 30 distinct phytochemical components, according to the results of the GC-MS analysis. The major phytoconstituents were n-Hexadecanoic acid (14.07), 1-(2-methylsulfanyl-ethyl)-2,8,9-trioxa (12.12), 9,12,15-Octadecatrienoic acid, (Z, Z, Z)- (11.97), Pregn-5-en-3-ol, 20-methyl-21-[3-methyl- (11.88) and Phytol (10.04). Using the disc diffusion technique, the plant extracts were made in ethanolic extracts to test their antibacterial efficacy against B. subtilis and S. aureus bacterial pathogens. Staphylococcus aureus had the highest zone of inhibition and the greatest activity among the S. trilobatum leaves employed for antibacterial study. Therefore, the plant's medicinal properties may be due to the presence of these phytochemicals.