Anxiety and nonpsychotic mental disorders in acute urticaria
Our findings reveal significant associations between AU and various mental health disorders, particularly anxiety and personality disorders. These associations suggest a complex bidirectional relationship mediated through psychoneuroimmunological pathways involving the HPA axis, mast cell activation, and inflammatory cytokines. We recommend implementing specific screening tools (HADS, GAD-7) and a stepped-care approach for integrated dermatological and psychological management of AU patients.
Authors
- Shlomo Vinker (ORCID: https://orcid.org/0000-0001-9804-7103)
- Eli Magen (ORCID: https://orcid.org/0000-0002-7713-423X)
- Shai Ashkenazi (ORCID: https://orcid.org/0000-0001-7244-0679)
- Avivit Golan‐Cohen (ORCID: https://orcid.org/0000-0003-2406-6402)
- Eugene Merzon (ORCID: https://orcid.org/0000-0001-5469-0236)
- Ilan Green (ORCID: https://orcid.org/0000-0002-9435-7152)
- Iris Manor (ORCID: https://orcid.org/0000-0002-0642-0028)
- Ariel Israel (ORCID: https://orcid.org/0000-0003-4389-8896)
- Avi Yakov
- Israel Magen (ORCID: https://orcid.org/0009-0006-5236-8538)
- Abraham Weizman (ORCID: https://orcid.org/0000-0002-9765-8938)
- Akim Geishin
Institutions
- Ben-Gurion University of the Negev (IL)
- Tel Aviv University (IL)
- Assuta Medical Center (IL)
- Geha Mental Health Center (IL)
- Ariel University (IL)
- Clalit Health Services (IL)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2025-08-10
- DOI
- https://doi.org/10.1016/j.bbih.2025.101088
- Primary Topic
- Urticaria and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00