Diagnostic value of hemogram indices in inflammatory diseases of the abdominal cavity in children of early and preschool age

The article presents the results of determining the value of integral leukocyte indices for diagnosing acute appendicitis and functional bowel disorders. The study included children of the first 6 years of life with acute appendicitis (n = 25), functional digestive disorders (n = 35), and healthy control children (n = 50). 14 integral indices were calculated based on the data of a general blood test. It was revealed that in children with acute appendicitis, there is a significant change in the erythrocyte loading coefficient, leukocyte intoxication index and body resistance index (р < 0.01). This confirms the expediency of using these indicators to assess the severity of inflammation and endotoxicosis in children. The study did not reveal a diagnostic value of the cell-phagocytic index, the ratio of leukocytes to ESR, and the nuclear intoxication index in the studied groups.

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Publication Details

Journal
Practical medicine
Published
2025-01-01
DOI
https://doi.org/10.32000/2072-1757-2025-3-83-87
Primary Topic
Human Health and Disease
Type
article
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Diagnostic value of hemogram indices in inflammatory diseases of the abdominal cavity in children of early and preschool age

Р. Ф. Махмутов
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Practical medicine
Human Health and Disease
article

Diagnostic value of hemogram indices in inflammatory diseases of the abdominal cavity in children of early and preschool age

Р. Ф. Махмутов
article en

Abstract

The article presents the results of determining the value of integral leukocyte indices for diagnosing acute appendicitis and functional bowel disorders. The study included children of the first 6 years of life with acute appendicitis (n = 25), functional digestive disorders (n = 35), and healthy control children (n = 50). 14 integral indices were calculated based on the data of a general blood test. It was revealed that in children with acute appendicitis, there is a significant change in the erythrocyte loading coefficient, leukocyte intoxication index and body resistance index (р < 0.01). This confirms the expediency of using these indicators to assess the severity of inflammation and endotoxicosis in children. The study did not reveal a diagnostic value of the cell-phagocytic index, the ratio of leukocytes to ESR, and the nuclear intoxication index in the studied groups.

Practical medicineVol. 23(3)
Good health and well-being
Openalex Percentile: Top 70%
Human Health and Disease
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