Effect of MicroRNA on Tumor Microenvironment During Bone Metastasis in Breast Cancer

One of the most prevalent types of cancer worldwide is breast cancer (BC), with hundreds of thousands of women dying from BC each year. Among them, bone metastasis which occurs frequently in the advanced stage of BC is the main cause of death in BC patients, and MicroRNA is involved in this process and significantly changes the tumor micro environment (TME). In current clinical treatments, some therapies are used to inhibit bone metastasis in BC, and it has been proposed that microRNA is crucial to the development of BC. However, these studies can only improve the patients' quality of life or detect the period of BC, lack of practical therapeutic significance. In this paper, TME in BC bone metastasis is analyzed to explore the relationship between microRNA and BC, and to obtain MicroRNA's function in altering TME during BC bone metastasis. This provides a new idea and reference for controlling the phenotype and symptoms of BC by regulating the expression level of Micro RNA in the future, but there is no effective method to accurately deliver Micro RNA to the human body, and future research can focus on this region.