The parallel mediation effects of nutrition, physical activity on depression and sarcopenia risk among older people with diabetes
A significant proportion of older adults with diabetes were found to be at high risk of sarcopenia, which underscores the importance of routine screening for sarcopenia risk in older adults with diabetes. Depression was strongly associated with sarcopenia risk, with nutrition and physical activity acting as parallel mediators in this relationship. Given the pivotal role of nutrition in this parallel mediation model, the implementation of individualized nutrition plans is crucial for preventing muscle loss and reducing the risk of sarcopenia.
Authors
- Cheng Li (ORCID: https://orcid.org/0000-0002-2874-6731)
- Xiling Hu (ORCID: https://orcid.org/0000-0001-7888-2267)
- Miaomiao Wang (ORCID: https://orcid.org/0000-0002-2254-4311)
- Qiao Liu (ORCID: https://orcid.org/0000-0002-6620-1994)
- Guo Xiaodi
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- Sias University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-08-11
- DOI
- https://doi.org/10.3389/fpubh.2025.1655640
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Sun Yat-sen University
- Fundamental Research Funds for the Central Universities
- Basic and Applied Basic Research Foundation of Guangdong Province