Long-term behaviour of non-functioning pituitary microadenomas: experience from a tertiary care centre in Romania

Micro-NFPAs have an overall benign clinical course, with a high measuring variability in tumors smaller than 6 mm and hypopituitarism is a very rare occurrence. Performing the first follow-up MRI at one year and if stable, delaying re-evaluation to 5 years, without pituitary function reassessment in absence of clinical manifestations, is a safe and cost-effective approach.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-08-11
DOI
https://doi.org/10.3389/fendo.2025.1613239
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Long-term behaviour of non-functioning pituitary microadenomas: experience from a tertiary care centre in Romania

Mădălina Elena Iftimie, Stella Pigni, Iulia Florentina Burcea, Ramona Dobre et al.
Frontiers in Endocrinology
Pituitary Gland Disorders and Treatments
article

Long-term behaviour of non-functioning pituitary microadenomas: experience from a tertiary care centre in Romania

Mădălina Elena Iftimie, Stella Pigni, Iulia Florentina Burcea, Ramona Dobre, Flavia Prodam, Cătălina Poiană
article en

Abstract

Micro-NFPAs have an overall benign clinical course, with a high measuring variability in tumors smaller than 6 mm and hypopituitarism is a very rare occurrence. Performing the first follow-up MRI at one year and if stable, delaying re-evaluation to 5 years, without pituitary function reassessment in absence of clinical manifestations, is a safe and cost-effective approach.

Frontiers in EndocrinologyVol. 16
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT), Carol Davila University of Medicine and Pharmacy (RO), Institutul Național de Endocrinologie C.I. Parhon (RO)
Good health and well-being
Openalex Percentile: Top 71%
Pituitary Gland Disorders and Treatments
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