Large animal model validation of a fenestrated balloon-expandable stent for treatment of aortoiliac occlusive disease
The AortoIliac FENestrated (AIFEN) stent is a novel device that is designed for the endovascular management of aortoiliac occlusive disease while maintaining the natural aortoiliac anatomy and native bifurcation. Here, we report the first benchtop creation of this device through modification of a balloon-expandable covered stent and implanted in three large animal porcine aortoiliac segments. AIFEN stent placement was feasible and was maintained for 4 weeks in vivo. This first proof-of-concept AIFEN stent study demonstrates promising results and warrants further, rigorous evaluation to improve endovascular management of aortoiliac occlusive disease.
Authors
- Santiago Elizondo Benedetto (ORCID: https://orcid.org/0000-0002-0911-8086)
- Mohamed A. Zayed (ORCID: https://orcid.org/0000-0001-6443-4527)
- Batool Arif (ORCID: https://orcid.org/0009-0006-3610-0865)
- Shahab Hafezi (ORCID: https://orcid.org/0000-0003-1832-8517)
- Maxwell C. Braasch (ORCID: https://orcid.org/0000-0002-6759-5593)
- John Cashin
- Guy M. Genin (ORCID: https://orcid.org/0000-0003-3612-4729)
- DeVaughn Rucker
- Mohamed Zaghloul (ORCID: https://orcid.org/0000-0002-4703-2662)
- Sophia R. Pyeatte
Institutions
- Washington University in St. Louis (US)
Publication Details
- Journal
- Journal of Vascular Surgery Cases and Innovative Techniques
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1016/j.jvscit.2025.101950
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Washington University in St. Louis
- National Institutes of Health
- National Heart, Lung, and Blood Institute