Expanding the silyl-Prins toolbox: selective access to C4-quaternary stereocenters in tetrahydropyrans using internal cyclopropylsilyl alcohols
The use of internal cyclopropylsilyl alcohols in Prins cyclization is reported as a methodology for the stereoselective construction of tetrahydropyrans bearing a quaternary stereocenter.
Authors
- Alberto Cherubin
- Asunción Barbero (ORCID: https://orcid.org/0000-0001-6825-7775)
- Paula González-Andrés (ORCID: https://orcid.org/0000-0003-0349-984X)
Institutions
- Universidad de Valladolid (ES)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00984g
- Primary Topic
- Synthetic Organic Chemistry Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00