Accelerated biological aging as a potential mediator mediates the relationship between metabolic syndrome and the risk of psoriasis: a prospective analysis from the UK biobank
MetS and its components play a key role in psoriasis development, especially in genetically susceptible individuals. Accelerated aging may partially explain this link, suggesting a potential biological pathway and underscoring the importance of early MetS identification.
Authors
- Liehua Deng
- Haibo Yu (ORCID: https://orcid.org/0000-0003-1506-2346)
- Jun Lyu (ORCID: https://orcid.org/0000-0002-2237-8771)
- Shuo Qiu (ORCID: https://orcid.org/0009-0008-4804-8640)
- Jinrong Zhang (ORCID: https://orcid.org/0000-0003-0774-8479)
- Ming Chen (ORCID: https://orcid.org/0000-0002-9677-1699)
- Rongqian Tian
- W. Y. Lau
Institutions
- Xinjiang Medical University (CN)
- Jinan University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Guangzhou Institute of Dermatology (CN)
- First Affiliated Hospital of Jinan University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1620027
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00