Deletion of the E3 ubiquitin ligase LRSAM1 fosters intracellular Staphylococcus aureus survival
The results indicate a significant role of LRSAM1 in the clearance of intracellular <i>S. aureus</i>. This contributes to a deeper understanding of the host cellular responses to <i>S. aureus</i> infection and will facilitate the development of novel therapeutic strategies to combat intracellularly persistent <i>S. aureus</i>.
Authors
- Clemens Cammann (ORCID: https://orcid.org/0009-0008-1699-0607)
- Hannes Wolfgramm (ORCID: https://orcid.org/0000-0002-6028-0046)
- Ulrike Seifert (ORCID: https://orcid.org/0000-0003-1037-3487)
- Karsten Becker (ORCID: https://orcid.org/0000-0002-6391-1341)
- Kristin Surmann (ORCID: https://orcid.org/0009-0009-7305-3457)
- Abhishek Kumar Singh (ORCID: https://orcid.org/0000-0002-4523-6055)
- Barbara M. Bröker (ORCID: https://orcid.org/0000-0002-5020-8542)
- Uwe Völker (ORCID: https://orcid.org/0000-0002-5689-3448)
- Ole Plöhn
- Clara Greger
- Madina Baglanova
Institutions
- Friedrich-Loeffler-Institut (DE)
- Universitätsmedizin Greifswald (DE)
- Universität Greifswald (DE)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.3389/fcimb.2025.1597830
- Citations
- 3
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Deutsche Forschungsgemeinschaft