Two sides of the coin: coagulation and inflammation in deep vein thrombosis – a prospective study on D-dimer and SIRI

This study demonstrated that inflammatory markers, particularly SIRI, were elevated in patients with deep vein thrombosis (DVT) and carried high predictive value in this patient group. The combined use of SIRI and D-dimer provided high diagnostic accuracy for DVT. SIRI, a low-cost index calculable through routine blood tests, was shown to be more effective than other inflammatory markers in predicting DVT. Additionally, the combination of SIRI and D-dimer yielded high positive and negative predictive values for DVT diagnosis.