Epidemiological and clinical impact of hepatitis E virus coinfection in chronic hepatitis B infected patients in Hebei, China
Our findings demonstrated an 18.70% seroprevalence of anti-HEV antibodies among chronically HBV-infected patients in the Hebei Province, with a significantly higher risk of coinfection in older individuals. HBV/HEV coinfection may aggravate liver injury and impair coagulation. These results provide valuable insights into the epidemiology and clinical consequences of HBV/HEV coinfection in this region.
Authors
- Fumin Feng (ORCID: https://orcid.org/0000-0001-6506-2235)
- Ying Chen (ORCID: https://orcid.org/0000-0001-6720-353X)
- Jianhua Lu
- Erhei Dai (ORCID: https://orcid.org/0000-0001-8835-6199)
- Yang Li (ORCID: https://orcid.org/0000-0002-4229-9800)
- Yun Guo (ORCID: https://orcid.org/0000-0002-1667-0186)
- Yuchen Xie (ORCID: https://orcid.org/0009-0008-0891-9288)
- Huixia Gao
- Yuzhu Shi
Institutions
- North China University of Science and Technology (CN)
- Hebei University of Science and Technology (CN)
- Fifth Hospital of Shijiazhuang (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.3389/fmicb.2025.1638614
- Citations
- 1
- Primary Topic
- Hepatitis Viruses Studies and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Health Commission of Hebei Province