Inflammatory mediators and the RAGE pathway in placental tissues of pregnancies complicated by severe preeclampsia
This study provides insight into the relationship of tissue inflammatory mediators with severe preeclampsia and the RAGE associated signaling complex, suggesting a pathogenic role for this pathway which has clinical implications for the understanding, diagnosis, and potential novel therapeutic approaches to the syndrome.
Authors
- Andrea R. Thurman (ORCID: https://orcid.org/0000-0001-9826-6664)
- Thomas Kimble (ORCID: https://orcid.org/0000-0002-6811-4894)
- Neelima Chandra
- Andrew Wong (ORCID: https://orcid.org/0000-0002-0902-3159)
- K. Heim (ORCID: https://orcid.org/0000-0003-3322-7423)
- Sharon M. Anderson (ORCID: https://orcid.org/0000-0003-2846-4109)
- Gustavo F. Doncel (ORCID: https://orcid.org/0009-0009-9641-1325)
Institutions
- Eastern Virginia Medical School (US)
- Instituto Benjamin Constant (BR)
- Old Dominion University (US)
Publication Details
- Journal
- Frontiers in Reproductive Health
- Published
- 2025-08-11
- DOI
- https://doi.org/10.3389/frph.2025.1587699
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00