Comparison of In-Hospital Mortality and Complications of Primary Percutaneous Coronary Intervention in Diabetics and Non-diabetic patients at a large Tertiary care hospital.

Abstract Background: Ischemic heart disease is the leading cause of death in Pakistan. We aimed to compare in-hospital mortality and complications of Primary Percutaneous Coronary Intervention (PCI) in diabetics and non-diabetic patients who had a diagnosis of ST-elevation myocardial infarction. Methods: This cross-sectional study was conducted at a tertiary care hospital and involved 560 patients. The patients were divided into diabetic and non-diabetic groups. Demographics, characteristics, risk factors, coronary vessel details, and post-PCI complications were compared between the groups. Results: The mean age of 560 patients was 52.17±11.5, of which males comprise 88.6%. Premature coronary disease and hypertension were more prominent in diabetics, while the percentage of smokers was higher in the non-diabetic group. No statistical significance was noted in the severity of stenosis or culprit vessels between groups. The incidence of post-PCI complications was insignificant among both groups. TIMI 0 and 3 are more prevalent in the non-diabetics group, while TIMI 1 and 2 were common in diabetics. Conclusion: In this single-center study, There was no significant difference noted in-hospital mortality and other post-PCI complications between both groups. Further multicenter, prospective, and larger sample-size studies are needed.