Severe Hemoperitoneum: Spontaneous Rupture of Uterine Leiomyosarcoma: A Rare Case

Uterine sarcomas, unlike the more prevalent leiomyomas, are not common. leiomyosarcoma tends to exhibit aggressive behavior and is associated with a worse prognosis. Leiomyomas are notably linked to uterine rupture with hemoperitoneum. Here, we present a rare case of spontaneous rupture of uterine leiomyosarcoma. A 44-year-old woman with multiple childbirths reported abdominal pain. A clinical examination indicated a large abdominal mass. After active resuscitation, Computed Tomography (CT) revealed an accumulation of intraperitoneal fluid and a heterogeneous mass in the uterus. The patient underwent emergency laparotomy and total hysterectomy due to a ruptured leiomyoma. The final pathology confirmed the diagnosis of leiomyosarcoma. Bleeding was a result of infarction and ulceration or ruptured superficial veins caused by elevated intra-abdominal pressure. Spontaneous hemorrhage from a uterine leiomyosarcoma leading to hemoperitoneum is rare. This condition should be considered in the differential diagnosis of gynecological emergencies.

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Publication Details

Journal
Journal of Obstetrics Gynecology and Cancer Research
Published
2025-08-03
DOI
https://doi.org/10.24200/jogcr.10.9.727
Primary Topic
Uterine Myomas and Treatments
Type
article
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article

Severe Hemoperitoneum: Spontaneous Rupture of Uterine Leiomyosarcoma: A Rare Case

Nema Mohamadian Roshan, Malihe Hasanzadeh, Anahita Hamidi Loyen, Mohadeseh Nazari Fathabad et al.
Journal of Obstetrics Gynecology and Cancer Research
Uterine Myomas and Treatments
article

Severe Hemoperitoneum: Spontaneous Rupture of Uterine Leiomyosarcoma: A Rare Case

Nema Mohamadian Roshan, Malihe Hasanzadeh, Anahita Hamidi Loyen, Mohadeseh Nazari Fathabad, Matin Moloudian
article en

Abstract

Uterine sarcomas, unlike the more prevalent leiomyomas, are not common. leiomyosarcoma tends to exhibit aggressive behavior and is associated with a worse prognosis. Leiomyomas are notably linked to uterine rupture with hemoperitoneum. Here, we present a rare case of spontaneous rupture of uterine leiomyosarcoma. A 44-year-old woman with multiple childbirths reported abdominal pain. A clinical examination indicated a large abdominal mass. After active resuscitation, Computed Tomography (CT) revealed an accumulation of intraperitoneal fluid and a heterogeneous mass in the uterus. The patient underwent emergency laparotomy and total hysterectomy due to a ruptured leiomyoma. The final pathology confirmed the diagnosis of leiomyosarcoma. Bleeding was a result of infarction and ulceration or ruptured superficial veins caused by elevated intra-abdominal pressure. Spontaneous hemorrhage from a uterine leiomyosarcoma leading to hemoperitoneum is rare. This condition should be considered in the differential diagnosis of gynecological emergencies.

Journal of Obstetrics Gynecology and Cancer ResearchVol. 10(9)
Mashhad University of Medical Sciences (IR)
Openalex Percentile: Top 74%
Uterine Myomas and Treatments
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