An Association Between Possible Sarcopenia as an Early Marker and Mild Cognitive Impairment: A Cross-Sectional Study

<b>Background/Objectives</b>: The purpose of this study is to investigate the association between possible sarcopenia, considered as an early marker before its diagnosis, and mild cognitive impairment. <b>Methods</b>: A cross-sectional study was conducted involving 60 physically inactive participants aged 40-69. Assessments included body composition, physical activity, and cognitive evaluations. The association between sarcopenia and mild cognitive impairment was examined using binary logistic regression, with odds ratios (ORs) and 95% confidence intervals (CIs) reported. <b>Results</b>: Participants with possible sarcopenia were found to have a 12.25 times higher risk of developing mild cognitive impairment (OR: 12.250; 95% CI: 1.692-88.711; <i>p</i> = 0.013). <b>Conclusions</b>: The findings highlight the critical role of early diagnosis of and intervention in sarcopenia to prevent cognitive decline. Future longitudinal studies are necessary to clarify causal relationships and optimize preventive strategies.