Literature Review: Zinner Syndrome

Zinner Syndrome (ZS) is a rare congenital anomaly defined by a triad: unilateral renal agenesis, an ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction. First reported by Zinner in 1914, the syndrome is considered the male equivalent of Mayer-Rokitansky-K?ster-Hauser (MRKH) syndrome in females. Due to its nonspecific presentation and low prevalence, it is often underdiagnosed. This review presents a comprehensive overview of the embryological basis, clinical manifestations, diagnostic approaches, and current management options for Zinner Syndrome, while also addressing recent advances and the impact on fertility.