Efficacy of CECT in Diagnosis of Hepatocellular Carcinoma with Histopathogical Correlation

Introduction Hepatocellular carcinoma (HCC) is a primary liver cancer that originates in the hepatocytes, the main functional cells of the liver. The advancements of Computed Tomography (CT) play major role in detecting liver pathologies. Injection of contrast media is primary while imaging liver region, So Contrast Enhanced Computed Tomography (CECT) is the best choice for this imaging. Though, CECT performed with hepatocellular carcinoma plays important role in assessing the size, margins and relationship with other structures.  Methods The retrospective observational crossover study included 30 patients who undergone for Contrast Enhanced Computed Tomography in department of Radio-Diagnosis at saveetha Medical College & Hospital. Patient demographics were analyzed & Chi-square test was used to perform statistical analysis for hypothesis.  Results The study included 24 males and 6 females with mean age of 40 years. Histopathology examination revealed 22 cases of HCC, out of which 19 were provisionally diagnosed in CECT.Out of this 22 patients, 16 were male and 6 were female, revolving a significant male gender predisposition.  Discussion The use of CECT improves lesion detection, size, type of carcinoma .This re -emphasizes the fact that male have significantly higher risk of liver cancer whichcomposed to females. Multiple diagnosis like alcohol consumption coupled with cirrhosis, hepatitis B and Hepatitis C infection, increased iron storage level have been postulated for males having a higher predisposition for HCC than females.  Conclusion The diagnosis of hepatocellular carcinoma and co-relation with histopathology contrast enhanced CT and conventional contrast enhanced CT, both performs equal role in detecting pathologies in the Abdomen region. Applying the correct useful technique in the region of interest helps to demonstrate the anatomical position and nature of the pathology.