The Partial Mediating Role of Arterial Stiffness in the Association Between Systemic Inflammation and Declining Renal Function in Type 2 Diabetes Mellitus: A Cross-Sectional Study
AASI partially mediates the association between NLR and eGFR in T2DM patients, providing new insights into the pathophysiological links between inflammation, vascular dysfunction, and kidney damage. Therapeutic strategies targeting inflammation and arterial stiffness might offer synergistic benefits for preserving renal function.
Authors
- Xin Dong (ORCID: https://orcid.org/0000-0002-5400-1872)
- Li Zhao (ORCID: https://orcid.org/0000-0002-6924-7146)
- Liangliang Zhu (ORCID: https://orcid.org/0000-0001-5627-3348)
- Lihui Wang (ORCID: https://orcid.org/0000-0001-8960-8642)
- Yanan Guo (ORCID: https://orcid.org/0000-0001-8592-6993)
Institutions
- Cangzhou Central Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/jir.s537949
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00