Characterization and management of patients with hereditary factor X deficiency: A case series
HFXD presents with variable bleeding phenotypes that may not correlate with FX:C levels. This analysis demonstrates that while bleeding phenotypes generally align with the revised EN-RBD classification, patients with mild or moderate HFXD can experience significant bleeding. Future work should focus on correlating genotype with phenotype and refining management guidelines for mild and moderate HFXD.
Authors
- Mark T. Reding (ORCID: https://orcid.org/0000-0003-3319-2806)
- Meera Chitlur (ORCID: https://orcid.org/0000-0001-7656-0694)
- Lauren E. Amos (ORCID: https://orcid.org/0000-0002-3357-898X)
- Cynthia Sabo (ORCID: https://orcid.org/0000-0002-4425-2248)
- Suchitra S. Acharya (ORCID: https://orcid.org/0009-0002-2782-6737)
Institutions
- Children's Mercy Hospital (US)
- Cohen Children's Medical Center (US)
- Children's Hospital of Michigan (US)
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- Transfusion
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1111/trf.18377
- Citations
- 1
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.77