Changes in non-culprit coronary lesions with PCSK9 inhibitors: the randomised, placebo-controlled FITTER trial
In patients with ACS and relevant non-culprit coronary artery lesions, the addition of evolocumab to HIST for 12 weeks, compared to placebo, did not result in improvement of FFR or maxLCBI<sub>4mm</sub>. (ClinicalTrials.gov: NCT04141579).
Authors
- Tim J.F. ten Cate
- Aysun Cetinyurek‐Yavuz (ORCID: https://orcid.org/0000-0003-4024-8775)
- Marleen van Wely (ORCID: https://orcid.org/0000-0003-4579-111X)
- Alexander Ijsselmuiden
- Rohit M. Oemrawsingh (ORCID: https://orcid.org/0000-0002-3617-3929)
- Aukelien C. Dimitriu‐Leen (ORCID: https://orcid.org/0000-0001-9131-9903)
- Himanshu Rai (ORCID: https://orcid.org/0000-0003-3917-1934)
- Robert‐Jan van Geuns (ORCID: https://orcid.org/0000-0003-2943-5932)
- Peter Damman (ORCID: https://orcid.org/0000-0002-9284-7967)
- Diederik F. van Wijk (ORCID: https://orcid.org/0000-0002-6961-5076)
- Martijn Meuwissen (ORCID: https://orcid.org/0000-0002-5421-5205)
- Clemens von Birgelen (ORCID: https://orcid.org/0000-0002-5128-2832)
- Valeria Paradies (ORCID: https://orcid.org/0000-0003-3513-7819)
- Frans B. Mensink (ORCID: https://orcid.org/0009-0001-8482-0588)
- J. Los (ORCID: https://orcid.org/0000-0002-6731-0965)
- Cyril Camaro (ORCID: https://orcid.org/0000-0001-6170-8318)
- Lokien X. van Nunen (ORCID: https://orcid.org/0000-0003-4650-5381)
- Pieter C. Smits (ORCID: https://orcid.org/0000-0002-9164-720X)
- Jin M. Cheng
- Robert A Byrne
- Mohamed M Reda Abdelaziz Morsy (ORCID: https://orcid.org/0009-0001-2519-0301)
- Niels van Royen
- Dirk J van Wijk
Institutions
- Radboud University Nijmegen (NL)
- Medisch Spectrum Twente (NL)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
- Albert Schweitzer Ziekenhuis (NL)
- Medisch Centrum Haaglanden (NL)
- Amphia Ziekenhuis (NL)
- Maasstad Ziekenhuis (NL)
- Assiut University (EG)
Publication Details
- Journal
- EuroIntervention
- Published
- 2025-08-01
- DOI
- https://doi.org/10.4244/eij-d-24-01065
- Citations
- 5
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 10.03