Unveiling the Therapeutic Potential of Jiawei Jianpi Huoyu Formula in Ulcerative Colitis: A Multi-Strategies and Experimental Study Integrating Network Pharmacology, Machine Learning, and Mendelian Randomization

These findings highlight the innovative application of MR in JJHF research and underscore its multi-component, multi-target mechanisms in UC treatment, particularly through anti-inflammatory pathways and modulation of HSPA5 signaling. This study lays a scientific foundation for the clinical application and mechanistic exploration of JJHF in managing UC, offering potential advantages over standard therapies like mesalazine.