Understanding Cutaneous Mastocytosis: A Case Report on the Symptoms and Diagnosis of a Rare Disease

Cutaneous mastocytosis is a rare skin condition characterized by the accumulation of mast cells, particularly in the dermis, affecting both children and adults. In children, cutaneous mastocytosis is more common, while in adults, it usually progresses to systemic mastocytosis. We present a case report of a three-year-old male child who presented with multiple itchy lesions all over the body for two and a half years. The lesions were spontaneous in nature, reddish in colour, with a wheal-like appearance. The purpose of the case report is to increase awareness and knowledge amongst pathologists about rare disorders.

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Publication Details

Journal
Cureus
Published
2025-08-11
DOI
https://doi.org/10.7759/cureus.89797
Primary Topic
Mast cells and histamine
Type
article
Field-Weighted Citation Impact
0.00
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article

Understanding Cutaneous Mastocytosis: A Case Report on the Symptoms and Diagnosis of a Rare Disease

Parineeta Shelke, Preeti Doshi, Purva Kulkarni, Reena Bharadwaj et al.
Cureus
Mast cells and histamine
article

Understanding Cutaneous Mastocytosis: A Case Report on the Symptoms and Diagnosis of a Rare Disease

Parineeta Shelke, Preeti Doshi, Purva Kulkarni, Reena Bharadwaj, Prima Selugar
article en

Abstract

Cutaneous mastocytosis is a rare skin condition characterized by the accumulation of mast cells, particularly in the dermis, affecting both children and adults. In children, cutaneous mastocytosis is more common, while in adults, it usually progresses to systemic mastocytosis. We present a case report of a three-year-old male child who presented with multiple itchy lesions all over the body for two and a half years. The lesions were spontaneous in nature, reddish in colour, with a wheal-like appearance. The purpose of the case report is to increase awareness and knowledge amongst pathologists about rare disorders.

CureusVol. 17(8)
Bharati Vidyapeeth (Deemed to be University) (IN)
Zero hunger
Openalex Percentile: Top 77%
Mast cells and histamine
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