Melatonin ameliorates zearalenone-induced ovarian damage in mice through antioxidative effects

MT protects against ZEN-induced ovarian and cellular damage by reducing oxidative stress and modulating the ATM-Chk2-p53 pathway. These findings highlight MT's potential as a protective feed additive against mycotoxin-related reproductive toxicity.

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Publication Details

Journal
Frontiers in Veterinary Science
Published
2025-08-11
DOI
https://doi.org/10.3389/fvets.2025.1587391
Primary Topic
Selenium in Biological Systems
Type
article
Field-Weighted Citation Impact
0.00

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article

Melatonin ameliorates zearalenone-induced ovarian damage in mice through antioxidative effects

C. Liu, Lei Song, Yi Song, Zhifang Zhao et al.
1 links
Frontiers in Veterinary Science
Selenium in Biological Systems
article

Melatonin ameliorates zearalenone-induced ovarian damage in mice through antioxidative effects

C. Liu, Lei Song, Yi Song, Zhifang Zhao, Wen‐Jie Jiang, Zhengtang Qi, Wanjing Wang, Xiaoyue Ma, Jianxiu Ma, Ling Fu, Yanqing Ma, Jin Zhao, Zhong Guo, Tianhao Wei
article en

Abstract

MT protects against ZEN-induced ovarian and cellular damage by reducing oxidative stress and modulating the ATM-Chk2-p53 pathway. These findings highlight MT's potential as a protective feed additive against mycotoxin-related reproductive toxicity.

Frontiers in Veterinary ScienceVol. 12
Minzu University of China (CN), Gansu Agricultural University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 75%
Selenium in Biological Systems
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Melatonin ameliorates zearalenone-induced ovarian damage in mice through antioxidative effects — C. Liu, Lei Song, et al. · Frontiers in Veterinary Science (2025) | TGRS Research Map | TGRS