Left atrial appendage closure versus anticoagulation in the management of atrial fibrillation: a systematic review, meta-analysis, and meta-regression analysis

LAAC has comparable efficacy in preventing strokes. The risk of CV death, all-cause deaths, and nonprocedural relevant bleeding, all of which are associated with the composite primary outcome is lower in the LAAC group versus the oral anticoagulation therapy and can have even greater efficacy with a longer follow-up period.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2025-08-11
DOI
https://doi.org/10.1097/ms9.0000000000003703
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Left atrial appendage closure versus anticoagulation in the management of atrial fibrillation: a systematic review, meta-analysis, and meta-regression analysis

Pugazhendi Inban, Jobby John, Gurmehar Singh, Sai Harini Chandrasekaran et al.
Annals of Medicine and Surgery
Atrial Fibrillation Management and Outcomes
article

Left atrial appendage closure versus anticoagulation in the management of atrial fibrillation: a systematic review, meta-analysis, and meta-regression analysis

Pugazhendi Inban, Jobby John, Gurmehar Singh, Sai Harini Chandrasekaran, Chiranjeevee R Saravanan, Omniat Amir Hussin, A. Dinesh, Hyma Bamba
article en

Abstract

LAAC has comparable efficacy in preventing strokes. The risk of CV death, all-cause deaths, and nonprocedural relevant bleeding, all of which are associated with the composite primary outcome is lower in the LAAC group versus the oral anticoagulation therapy and can have even greater efficacy with a longer follow-up period.

Annals of Medicine and SurgeryVol. 87(10)
University of Khartoum (SD), Madras Medical College (IN), Kempegowda Institute of Medical Sciences (IN), St. Clare Hospital in Lakewood (US), Dr. Somervell Memorial CSI Medical College and Hospital (IN), The Future University (SD), Government Medical College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 67%
Atrial Fibrillation Management and Outcomes
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Left atrial appendage closure versus anticoagulation in the management of atrial fibrillation: a systematic review, meta-analysis, and meta-regression analysis — Pugazhendi Inban, Jobby John, et al. · Annals of Medicine and Surgery (2025) | TGRS Research Map | TGRS