Bayesian response adaptive randomization

I am planning a randomized trial to compare five different treatment strategies for breast cancer.To generate sufficient evidence for identifying the most effective treatment, an adequate number of patients will need to be enrolled in each arm.To improve efficiency and potentially reduce costs, I am considering using a design that incorporates Bayesian response adaptive randomization.Is this a viable and appropriate option for such a multi-arm trial?

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Publication Details

Journal
The Southwest Journal of Medicine
Published
2025-07-25
DOI
https://doi.org/10.12746/swjm.v13i56.1531
Primary Topic
Bayesian Methods and Mixture Models
Type
article
Field-Weighted Citation Impact
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article

Bayesian response adaptive randomization

Shengping Yang, Gilbert Berdine
The Southwest Journal of Medicine
Bayesian Methods and Mixture Models
article

Bayesian response adaptive randomization

Shengping Yang, Gilbert Berdine
article en

Abstract

I am planning a randomized trial to compare five different treatment strategies for breast cancer.To generate sufficient evidence for identifying the most effective treatment, an adequate number of patients will need to be enrolled in each arm.To improve efficiency and potentially reduce costs, I am considering using a design that incorporates Bayesian response adaptive randomization.Is this a viable and appropriate option for such a multi-arm trial?

The Southwest Journal of MedicineVol. 13(56)
Pennington Biomedical Research Center (US), Texas Tech University (US), Texas Tech University Health Sciences Center (US)
Openalex Percentile: Top 89%
Bayesian Methods and Mixture Models
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