Screening Actinomycetes extracts for antimicrobial compounds against methicillin-resistant Staphylococcus aureus and helper-compounds against aminoglycoside-resistant E. coli
Compounds with antibacterial and helper drug activity were identified using our screening approach. The results demonstrate the importance of strain selection in antimicrobial screening and highlight the potential of natural products as a source of potential new antibacterial and adjuvant therapies against both Gram-positive and Gram-negative bacteria.
Authors
- Salvatore Pisanu (ORCID: https://orcid.org/0000-0002-8174-046X)
- S. Wellner (ORCID: https://orcid.org/0009-0006-2294-7264)
- Stefano Donadio (ORCID: https://orcid.org/0000-0002-2121-8979)
- Daniela Pagnozzi (ORCID: https://orcid.org/0000-0001-7764-1867)
- Sonia I. Maffioli
- John Elmerdahl Olsen (ORCID: https://orcid.org/0000-0001-6225-6587)
- Sergio Uzzau (ORCID: https://orcid.org/0000-0001-6246-2794)
- Margherita Sosio (ORCID: https://orcid.org/0000-0003-4297-6936)
- Dina Al Nahhas
Institutions
- University of Copenhagen (DK)
- University of Sassari (IT)
- Copenhagen Business School (DK)
- Frederiksberg Hospital (DK)
- Fincons Group (Italy) (IT)
- Sardegna Ricerche (Italy) (IT)
Publication Details
- Journal
- Open Research Europe
- Published
- 2025-08-11
- DOI
- https://doi.org/10.12688/openreseurope.19988.2
- Citations
- 1
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- European Commission
- Horizon 2020 Framework Programme