Cerebellar lesions caused by vitamin B12 deficiency: a case report

Vitamin B 12 deficiency can cause subacute combined degeneration of the spinal cord and cerebellar lesions. The patient, a 78-year-old woman, presented with an unstable gait, speech impairment and memory decline for one month. The neurological examination revealed ataxia, cerebellar speech disorder and mild cognitive impairment. Head and cervical vertebra magnetic resonance imaging (MRI) showed spinal cord and cerebellar lesions. The patient's symptoms improved after supplementation with vitamin B 12 . We found few reports of such cases in the literature. In this case report, we describe the entire diagnostic and treatment process of vitamin B 12 deficiency involving cerebellar lesions and briefly discuss the related pathogenesis, research progress and treatment.

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Publication Details

Journal
Folia Neuropathologica
Published
2025-01-01
DOI
https://doi.org/10.5114/fn.2025.152518
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cerebellar lesions caused by vitamin B12 deficiency: a case report

Xu Hong, Hong Miao, Yan Wu, Lina Qin et al.
Folia Neuropathologica
Folate and B Vitamins Research
article

Cerebellar lesions caused by vitamin B12 deficiency: a case report

Xu Hong, Hong Miao, Yan Wu, Lina Qin, L L Chen, Fang Li, Han Yang, Xin Hu, Juping Chen
article en

Abstract

Vitamin B 12 deficiency can cause subacute combined degeneration of the spinal cord and cerebellar lesions. The patient, a 78-year-old woman, presented with an unstable gait, speech impairment and memory decline for one month. The neurological examination revealed ataxia, cerebellar speech disorder and mild cognitive impairment. Head and cervical vertebra magnetic resonance imaging (MRI) showed spinal cord and cerebellar lesions. The patient's symptoms improved after supplementation with vitamin B 12 . We found few reports of such cases in the literature. In this case report, we describe the entire diagnostic and treatment process of vitamin B 12 deficiency involving cerebellar lesions and briefly discuss the related pathogenesis, research progress and treatment.

Folia NeuropathologicaVol. 63(3)
Nanjing University of Chinese Medicine (CN)
Zero hunger
Openalex Percentile: Top 68%
Folate and B Vitamins Research
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