Cerebellar lesions caused by vitamin B12 deficiency: a case report
Vitamin B 12 deficiency can cause subacute combined degeneration of the spinal cord and cerebellar lesions. The patient, a 78-year-old woman, presented with an unstable gait, speech impairment and memory decline for one month. The neurological examination revealed ataxia, cerebellar speech disorder and mild cognitive impairment. Head and cervical vertebra magnetic resonance imaging (MRI) showed spinal cord and cerebellar lesions. The patient's symptoms improved after supplementation with vitamin B 12 . We found few reports of such cases in the literature. In this case report, we describe the entire diagnostic and treatment process of vitamin B 12 deficiency involving cerebellar lesions and briefly discuss the related pathogenesis, research progress and treatment.
Authors
- Xu Hong (ORCID: https://orcid.org/0000-0002-5500-918X)
- Hong Miao (ORCID: https://orcid.org/0000-0003-4590-6781)
- Yan Wu (ORCID: https://orcid.org/0000-0002-2355-0887)
- Lina Qin (ORCID: https://orcid.org/0000-0002-6625-0198)
- L L Chen (ORCID: https://orcid.org/0009-0005-6304-9738)
- Fang Li (ORCID: https://orcid.org/0000-0002-7551-5899)
- Han Yang (ORCID: https://orcid.org/0000-0001-8994-7804)
- Xin Hu (ORCID: https://orcid.org/0000-0003-1430-0672)
- Juping Chen (ORCID: https://orcid.org/0000-0003-2077-2414)
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Folia Neuropathologica
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5114/fn.2025.152518
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00