The Impact of Social Determinants of Health on Quality of Life in a Cohort of 1300 Children With Epilepsy
In children with epilepsy, SDOH were associated with HRQoL, but to a lesser degree than epilepsy-related factors. Higher seizure burden, frequent ASM side effects, and developmental/learning issues had the largest association with lower HRQoL. This study highlights areas for intervention to improve HRQoL and indicates that HRQoL may not be a useful outcome measure to assess the impact of an intervention on SDOH.
Authors
- Kristen H. Arredondo (ORCID: https://orcid.org/0000-0001-6562-8331)
- Mariah Eisner (ORCID: https://orcid.org/0000-0002-4703-4342)
- Shivani Bhatnagar (ORCID: https://orcid.org/0000-0002-7604-4793)
- Christopher W. Beatty (ORCID: https://orcid.org/0000-0002-8352-6694)
- Ammar Shaikhouni (ORCID: https://orcid.org/0000-0002-3527-4920)
- Adam P. Ostendorf (ORCID: https://orcid.org/0000-0002-9994-6650)
- Stephanie M. Ahrens (ORCID: https://orcid.org/0000-0001-5551-2431)
- Jaime‐Dawn E. Twanow (ORCID: https://orcid.org/0000-0002-5398-9751)
- Nancy A. Auer (ORCID: https://orcid.org/0000-0002-0986-3166)
Institutions
- Nationwide Children's Hospital (US)
- The University of Texas at Austin (US)
Publication Details
- Journal
- Pediatric Neurology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1016/j.pediatrneurol.2025.08.004
- Citations
- 1
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Nationwide Children's Hospital