Malignant mimicry: A rare case of pulmonary mucoepidermoid carcinoma presenting as obstructive pneumonia

Pulmonary mucoepidermoid carcinomas (PMECs) are rare malignancies that often present with non-specific pulmonary symptoms and obstructive pneumonia. We present a 19-year-old female who presented with two years of recurrent pneumonia, dyspnea, and left-sided pleuritic pain. Review of serial ED imaging would identify a persistent lung infiltrate located in the left upper lobe. Bronchoscopy with extensive pathology analysis would confirm MAML2-positive stage IB mucoepidermoid carcinoma. The patient underwent curative treatment consisting of a sleeve lobectomy and was placed under close follow-up and monitoring. This case emphasizes the importance of having a high clinical index of suspicion with symptoms indicative of obstructive pneumonia in otherwise healthy young adults.

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Journal
Respiratory Medicine Case Reports
Published
2025-01-01
DOI
https://doi.org/10.1016/j.rmcr.2025.102277
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
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article
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article

Malignant mimicry: A rare case of pulmonary mucoepidermoid carcinoma presenting as obstructive pneumonia

Alfredo Iardino, Henry Elsenpeter, Kelly Reishus
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Respiratory Medicine Case Reports
Salivary Gland Tumors Diagnosis and Treatment
article

Malignant mimicry: A rare case of pulmonary mucoepidermoid carcinoma presenting as obstructive pneumonia

Alfredo Iardino, Henry Elsenpeter, Kelly Reishus
article en

Abstract

Pulmonary mucoepidermoid carcinomas (PMECs) are rare malignancies that often present with non-specific pulmonary symptoms and obstructive pneumonia. We present a 19-year-old female who presented with two years of recurrent pneumonia, dyspnea, and left-sided pleuritic pain. Review of serial ED imaging would identify a persistent lung infiltrate located in the left upper lobe. Bronchoscopy with extensive pathology analysis would confirm MAML2-positive stage IB mucoepidermoid carcinoma. The patient underwent curative treatment consisting of a sleeve lobectomy and was placed under close follow-up and monitoring. This case emphasizes the importance of having a high clinical index of suspicion with symptoms indicative of obstructive pneumonia in otherwise healthy young adults.

Respiratory Medicine Case ReportsVol. 57
University of North Dakota (US), North Dakota Department of Health (US), St. Alexius Heart and Lung Clinic (US)
Good health and well-being
Openalex Percentile: Top 66%
Salivary Gland Tumors Diagnosis and Treatment
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Malignant mimicry: A rare case of pulmonary mucoepidermoid carcinoma presenting as obstructive pneumonia — Alfredo Iardino, Henry Elsenpeter, et al. · Respiratory Medicine Case Reports (2025) | TGRS Research Map | TGRS