Very Late-Onset Lingual Necrosis Post-radiation in an Adult: A Case Report

Lingual necrosis is a rare but serious late complication of radiotherapy for head and neck cancer, despite the tongue's rich vascular supply. We report the case of a 59-year-old man who developed unilateral tongue necrosis 16 months after chemoradiotherapy for oropharyngeal carcinoma. A cervico-facial CT scan showed occlusion of the right lingual artery and compensatory dilation of collateral vessels. Surgical debridement of necrotic tissue was performed, and histopathology confirmed the lingual necrosis. The delayed onset and extent of necrosis in this case suggest progressive, radiation-induced microvascular injury. This case highlights the importance of prolonged follow-up and early recognition of atypical post-treatment lesions.

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Journal
Cureus
Published
2025-08-11
DOI
https://doi.org/10.7759/cureus.89828
Primary Topic
Head and Neck Cancer Studies
Type
article
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article

Very Late-Onset Lingual Necrosis Post-radiation in an Adult: A Case Report

Gaëtan Cavelier, Didier Dequanter, Lina Benchillal, Layal Abi-Khalil et al.
Cureus
Head and Neck Cancer Studies
article

Very Late-Onset Lingual Necrosis Post-radiation in an Adult: A Case Report

Gaëtan Cavelier, Didier Dequanter, Lina Benchillal, Layal Abi-Khalil, Lamia El Ouahabi
article en

Abstract

Lingual necrosis is a rare but serious late complication of radiotherapy for head and neck cancer, despite the tongue's rich vascular supply. We report the case of a 59-year-old man who developed unilateral tongue necrosis 16 months after chemoradiotherapy for oropharyngeal carcinoma. A cervico-facial CT scan showed occlusion of the right lingual artery and compensatory dilation of collateral vessels. Surgical debridement of necrotic tissue was performed, and histopathology confirmed the lingual necrosis. The delayed onset and extent of necrosis in this case suggest progressive, radiation-induced microvascular injury. This case highlights the importance of prolonged follow-up and early recognition of atypical post-treatment lesions.

CureusVol. 17(8)
Centre Hospitalier Universitaire de Saint-Pierre (BE)
Quality Education
Openalex Percentile: Top 72%
Head and Neck Cancer Studies
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Very Late-Onset Lingual Necrosis Post-radiation in an Adult: A Case Report — Gaëtan Cavelier, Didier Dequanter, et al. · Cureus (2025) | TGRS Research Map | TGRS