DYSBIOSIS IN THE DEVELOPMENT AND PROGRESSION OF MALIGNANT TUMOURS OF THE HUMAN DIGESTIVE SYSTEM

Malignant tumors are another cause of human death after heart disease. Along with long-known officials in the last ten years, robots have appeared that are associated with the influx of microbiome on the cause and progression of cancer. There is a lot of stupidity, a lot of friction, so that the direction begins to develop. In this review, we look at the influx of the microbiome into the origin and evolution of epithelial malignant tumors of the intestinal tract and related approaches to prevention. In this gallery llya Illich Mechnikov emphasized that the disruption of human microbiota plays a key role in the development of illness, which does not allow the biological age of the species to reach. According to the World Health Organization, probiotics are microorganisms that, when administered in an adequate amount, improve the health of the owner. An effective probiotic must meet the lowest criteria. This has the potential to bring obvious bark to the owner, to survive in the intestinal tract, resistance to hydrochloric acid in the gut, and inability to transfer genes of resistance to antibiotics.Porphyromonas gingivalis, Fusobacterium nucleatum, Prevotella sp., Alloprevotella sp., Capnocytophaga s, Streptococcus anginosus were found in empty mouth patients for oral cancer. It is not clear whether they are the initiators of microbiome change (drivers) or bacteria — passengers. Alloprevotella, Veillonella may be present before the development of carcinoma of the stomac. The most common microorganism isolated from malignant intestinal tumors is Fusobacterium Nucleatum. Dysbiosis in colorectal cancer is associated with a decrease in the number of L. gallinarum, Streptococcus thermophilus and an increase in Firmicutes and Bacteroidetes, as well as a decrease in bacterial diversity. Antagonistic bacteria are fermented milk flora, which correlates with diets rich in vegetables, fruits, peas, legumes and whole grain products. The mechanism by which the malignant growth and subsequent evolution of puffballs is overcome is a decrease in the pH of the colon.In the last ten years, Lactobacillus reuteri has become the most popular among both its predecessors and the population due to its ability to promote the acidity of the intestinal barrier. Lactobacilli have the assigned function of supporting the host’s immune system, lowering the pH of the intestines, and changing the level of inflammation. In addition, the authors found that these bacteria are more likely to renew the damaged intestinal epithelium by stimulating the proliferation of pre-committed cells to the intestine. Previously, we showed that in patients with stomac cancer in remission, sensitization to normal tissue occurred more often than in patients with an unfavorable prognosis (38.89% and 6%). Also, a higher level of sensitization to the normal mucous tissue of the pouch was an indicator of a best prognosis. It is now clear that the main role in the recovery of normal mucous tissue is played Lactobacillus reuteri.