Clinical Evaluation of Kofsap-Sf Cough Syrup for Persistent Cough Relief: A Pilot Study

Introduction: Persistent cough significantly impacts patient well-being. Traditional cough syrups often contain sugar, which can be unsuitable for diabetic or health-conscious individuals. Objective: To evaluate the clinical efficacy and safety of Kofsap-SF, a sugar-free herbal syrup, in relieving persistent cough and improving quality of life. Methods: An open-label, single-arm pilot study was conducted with 30 participants aged 35–60 years diagnosed with persistent cough. Participants received 10 ml of Kofsap-SF syrup three times daily for 2–4 weeks. Symptom severity and quality of life were assessed using the Cough-Specific Quality of Life Questionnaire (CQLQ). Results: The average symptom score decreased from 14 at baseline to 8 by Week 2 and 4 by Week 4. Quality of life scores improved from 10 to 4. 63% of participants showed significant symptom relief by Week 2; the remainder responded by Week 4. No adverse effects were reported. Conclusion: Kofsap-SF is an effective sugar-free herbal remedy for persistent cough, demonstrating symptom reduction and improved quality of life. Larger randomized trials are warranted.