Beyond traditional endpoints: A multi-state modelling approach to integrating morbidity and mortality in cancer treatments evaluation
Multi-state modelling offers a flexible way to integrate morbidity and mortality in evaluating cancer treatments. By capturing health trajectories and enabling utility-based assessments, it may complement traditional methods to inform treatment decisions.
Authors
- Kit C. B. Roes (ORCID: https://orcid.org/0000-0002-6775-1963)
- Francesco Pignatti (ORCID: https://orcid.org/0000-0001-9296-2474)
- Hans L. Hillege (ORCID: https://orcid.org/0000-0001-7397-1148)
- Jan J. Cornelissen (ORCID: https://orcid.org/0000-0002-1864-4598)
- Jan Bogaerts (ORCID: https://orcid.org/0000-0003-4216-3679)
- Douwe Postmus (ORCID: https://orcid.org/0000-0002-9458-7038)
Institutions
- European Medicines Agency (NL)
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- European Organisation for Research and Treatment of Cancer (BE)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1016/j.ejca.2025.115704
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00