Antioxidant, Antibacterial and Anti-Inflammatory Potential of Phytosynthesized Copper Nanoparticles by Using <i>Syzygium Cumini</i> Seed Extract

Nanotechnology involves the study of matter at the nanoscale level. Significant developments in nanotechnology have drawn a lot of interest in a range of biomedical applications. Synthesis of Syzygium cumini copper nanoparticles (SC-CuNPs) using S. cumini seed extract was primarily confirmed by the color change where light brown turns into dark brown, with sharp absorption maxima at 360 nm. Fourier Transform Infrared Spectroscopy revealed the various functional groups corresponding to the secondary metabolites that are responsible for the stabilization of SC-CuNPs, while X-ray diffraction analysis indicated a crystalline structure with an average particle size of 80 nm. SC-CuNPs were spherical, as revealed by the Scanning Electron Microscope analysis. At 125 μg/mL concentration, the SC-CuNPs exhibited significant antioxidant activity, as evidenced by 53% of hydrogen peroxide scavenging and 55% of free radical scavenging activity as measured by the phosphomolybdenum method. The antibacterial activity of SC-CuNPs revealed maximum zone of inhibition against Escherichia coli (28 ± 0.97 mm) and Staphylococcus aureus (32 ± 0.89 mm). Furthermore, SC-CuNPs demonstrated 43% anti-inflammatory activity at a 500 μg/mL concentration. The current work concludes by emphasizing the non-toxic and cost-effective properties of SC-CuNPs. Additionally, it presents an alluring and promising avenue for future applications in the biomedical field.