Comparative outcome analyses of subchondral <i>vs</i> intra-articular bone marrow aspirate concentrate in primary osteoarthritis knee: A double-blinded randomized controlled trial protocol
This trial aims to refine regenerative strategies for knee OA by comparing subchondral vs intra-articular BMAC injections, addressing long-term efficacy, safety, and treatment standardization to guide targeted interventions. This trial will provide critical insights into the comparative efficacy and safety of subchondral vs intra-articular BMAC injections in treating primary knee OA.
Authors
- R Rangarajan
- Arulkumar Nallakumarasamy (ORCID: https://orcid.org/0000-0002-2445-2883)
- Naveen Jeyaraman (ORCID: https://orcid.org/0000-0002-4362-3326)
- Sathish Muthu (ORCID: https://orcid.org/0000-0002-7143-4354)
- Sandeep Shrivastava (ORCID: https://orcid.org/0000-0001-6866-3423)
- Swaminathan Ramasubramanian (ORCID: https://orcid.org/0000-0001-8845-8427)
- Madhan Jeyaraman
Institutions
- Meenakshi Academy of Higher Education and Research (IN)
- Orthopaedic Research Group (IN)
- Meenakshi Medical College Hospital and Research Institute (IN)
Publication Details
- Journal
- World Journal of Experimental Medicine
- Published
- 2025-08-12
- DOI
- https://doi.org/10.5493/wjem.v15.i3.106020
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00