Inhibition of histone methyltransferase G9a promotes the osteogenic potential of bone-derived stem cells in diabetic-osteoporosis by regulating the LINC00657/miR-204-5p/IGFBP5 pathway
G9a inhibits the osteogenic potential of T2DM-BMSCs by regulating the LINC00657/miR-204-5p/IGFBP5 pathway and UNC0638 may be a potential agent for DOP treatment.
Authors
- Meng Qiao (ORCID: https://orcid.org/0000-0003-4628-1103)
- Shengyang Guo
- Jin‐Hu Fan (ORCID: https://orcid.org/0000-0003-3159-7893)
- Bin Wang (ORCID: https://orcid.org/0000-0003-0225-9393)
- Shaojun Wang (ORCID: https://orcid.org/0000-0003-0467-8911)
- Feng Gao (ORCID: https://orcid.org/0000-0001-9801-2285)
- Shengli Xia
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fendo.2025.1625944
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00