Safety and efficacy of autologous bone marrow aspirate concentrate injection for idiopathic male infertility: A comparative study

This trial highlights the potential of autologous BMAC as a promising therapeutic option for male infertility. Despite the absence of significant changes within individual treatment arms, BMAC therapy demonstrated superior efficacy in improving both sperm count and motility compared to standard pharmacotherapy and lifestyle modifications. These findings underscore the potential role of regenerative medicine in addressing severe oligospermia and azoospermia, warranting further research to solidify its clinical applicability.

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Publication Details

Journal
World Journal of Experimental Medicine
Published
2025-08-12
DOI
https://doi.org/10.5493/wjem.v15.i3.107323
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety and efficacy of autologous bone marrow aspirate concentrate injection for idiopathic male infertility: A comparative study

Arulkumar Nallakumarasamy, Naveen Jeyaraman, Sathish Muthu, Avinash Gandi Devadas et al.
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World Journal of Experimental Medicine
Sperm and Testicular Function
article

Safety and efficacy of autologous bone marrow aspirate concentrate injection for idiopathic male infertility: A comparative study

Arulkumar Nallakumarasamy, Naveen Jeyaraman, Sathish Muthu, Avinash Gandi Devadas, Swaminathan Ramasubramanian, Madhan Jeyaraman, Ravi Velamoor Rangarajan, Dhossaradhan Jayakumar Padmanapan
article en

Abstract

This trial highlights the potential of autologous BMAC as a promising therapeutic option for male infertility. Despite the absence of significant changes within individual treatment arms, BMAC therapy demonstrated superior efficacy in improving both sperm count and motility compared to standard pharmacotherapy and lifestyle modifications. These findings underscore the potential role of regenerative medicine in addressing severe oligospermia and azoospermia, warranting further research to solidify its clinical applicability.

World Journal of Experimental MedicineVol. 15(3)
Regenerative Medicine Institute (MX)
Good health and well-being
Openalex Percentile: Top 72%
Sperm and Testicular Function
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