Safety and efficacy of autologous bone marrow aspirate concentrate injection for idiopathic male infertility: A comparative study
This trial highlights the potential of autologous BMAC as a promising therapeutic option for male infertility. Despite the absence of significant changes within individual treatment arms, BMAC therapy demonstrated superior efficacy in improving both sperm count and motility compared to standard pharmacotherapy and lifestyle modifications. These findings underscore the potential role of regenerative medicine in addressing severe oligospermia and azoospermia, warranting further research to solidify its clinical applicability.
Authors
- Arulkumar Nallakumarasamy (ORCID: https://orcid.org/0000-0002-2445-2883)
- Naveen Jeyaraman (ORCID: https://orcid.org/0000-0002-4362-3326)
- Sathish Muthu (ORCID: https://orcid.org/0000-0002-7143-4354)
- Avinash Gandi Devadas
- Swaminathan Ramasubramanian (ORCID: https://orcid.org/0000-0001-8845-8427)
- Madhan Jeyaraman
- Ravi Velamoor Rangarajan
- Dhossaradhan Jayakumar Padmanapan
Institutions
- Regenerative Medicine Institute (MX)
Publication Details
- Journal
- World Journal of Experimental Medicine
- Published
- 2025-08-12
- DOI
- https://doi.org/10.5493/wjem.v15.i3.107323
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00