Oxytocin enhances oligodendrocyte development and improves social deficits in autistic rats
Our findings demonstrate that oxytocin significantly improve social interaction deficits in the VPA-induced autism model, which may be related to its activation of the PI3K/AKT pathway to promote oligodendrocyte development and differentiation.
Authors
- Bo Zhou (ORCID: https://orcid.org/0000-0003-0349-1610)
- Min Wen (ORCID: https://orcid.org/0000-0003-2220-7099)
- Hongbo R. Luo (ORCID: https://orcid.org/0000-0002-8545-0451)
- Yi Zhang (ORCID: https://orcid.org/0009-0000-8623-0867)
- Shuang Zheng
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fnins.2025.1624932
- Citations
- 1
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 2.44