Gut microbiota and their metabolites ameliorate acute and chronic colitis in mice via modulating Th17/Treg balance
The maintenance of an appropriate Th17/Treg equilibrium during microbiota restoration demonstrates therapeutic advantages. Notably, butyrate synergistically enhances microbial therapeutic effects, providing experimental evidence for personalized modulation of gut ecosystems in inflammatory bowel disease management.
Authors
- Huichao Zhang
- H Y Tao
- Xin Tan (ORCID: https://orcid.org/0000-0002-4528-1390)
- Dongyue Li (ORCID: https://orcid.org/0000-0002-7740-9686)
- Yue Lu (ORCID: https://orcid.org/0000-0002-1772-4844)
- Hao Ling
- Sok Theany
- Hongyu Xu (ORCID: https://orcid.org/0009-0006-0310-4763)
Institutions
- Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fmicb.2025.1643209
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61