Sequence-based prioritization of i-Motif candidates in the human genome
This work presents a scalable and statistically robust method to enrich for biologically relevant iM sequences, providing a valuable resource for future experimental validation and the rational design of ligands targeting iMs to modulate gene expression in contexts such as cancer.
Authors
- Mauro Fasano (ORCID: https://orcid.org/0000-0003-0628-5871)
- Veronica Remori
- Michela Prest
Institutions
- University of Insubria (IT)
- Ospedale di Circolo di Busto Arsizio (IT)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fbinf.2025.1657841
- Citations
- 1
- Primary Topic
- RNA and protein synthesis mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.81