Identification of the prognostic effect of mitophagy-related genes in acute myeloid leukemia
This study identified five mitophagy-related genes as prognostic biomarkers in AML and developed a robust risk model that correlates with survival outcome, immune infiltration, and drug sensitivity. These findings offer new insights into mitophagy-related mechanisms in AML and may guide personalized therapeutic strategies.
Authors
- Xiaoyun Wu
- Wenyuan Zhu
- Xuan Fan
- Baoxi Zhang (ORCID: https://orcid.org/0000-0001-7462-7592)
- Chaonan Li (ORCID: https://orcid.org/0000-0002-5514-842X)
- Haichao Zhao (ORCID: https://orcid.org/0000-0001-8434-0392)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1580597
- Citations
- 2
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 3.54
Funders
- Health Commission of Hebei Province
- Natural Science Foundation of Hebei Province