NcROP2 deletion reduces Neospora caninum virulence by altering parasite stage differentiation and hijacking host immune response
These findings highlight NcROP2 as a key virulence factor involved in immune evasion and parasite proliferation, providing new insights into <i>N. caninum</i> infection pathogenesis and potential avenues for vaccine development.
Authors
- David Arranz-Solís (ORCID: https://orcid.org/0000-0002-2647-3194)
- Musa A. Hassan (ORCID: https://orcid.org/0000-0002-0371-3300)
- Rafael Amieva (ORCID: https://orcid.org/0000-0002-9557-823X)
- Esther Collantes-Fernández (ORCID: https://orcid.org/0000-0002-1601-6889)
- Pilar Horcajo (ORCID: https://orcid.org/0000-0001-9758-7765)
- Montserrat Coronado (ORCID: https://orcid.org/0009-0004-5499-4132)
- Luis Miguel Ortega‐Mora (ORCID: https://orcid.org/0000-0002-4986-6783)
- Jessica Powell
Institutions
- Roslin Institute (GB)
- Department of Animal Health (VN)
- Centre for Immunity, Infection and Evolution (GB)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fimmu.2025.1617570
- Citations
- 1
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Comunidad de Madrid
- Ministerio de Ciencia, Innovación y Universidades