Prognostic role of angiotensin-II receptor type 1 and endothelin-1 receptor type A agonistic autoantibodies in patients with acute myocardial infarction

AT1R-AAs and ETAR-AAs are associated with an increased risk of MACE after STEMI. Assessment of autoantibody levels paves the way for future therapies targeting specific molecular pathways associated with poor prognosis after an acute coronary event.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2025-08-12
DOI
https://doi.org/10.3389/fcvm.2025.1515693
Primary Topic
Receptor Mechanisms and Signaling
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic role of angiotensin-II receptor type 1 and endothelin-1 receptor type A agonistic autoantibodies in patients with acute myocardial infarction

Francesco Tona, Martina Perazzolo Marra, Emanuele Cozzi, Giovanni Civieri et al.
Frontiers in Cardiovascular Medicine
Receptor Mechanisms and Signaling
article

Prognostic role of angiotensin-II receptor type 1 and endothelin-1 receptor type A agonistic autoantibodies in patients with acute myocardial infarction

Francesco Tona, Martina Perazzolo Marra, Emanuele Cozzi, Giovanni Civieri, Sabino Iliceto, Marta Vadori, Benedetta Schiavon, Giacomo Bernava, Giulia Masiero, Loira Leoni, Donatella Tansella, Laura Iop, Annagrazia Cecere, Marika Martini
article en

Abstract

AT1R-AAs and ETAR-AAs are associated with an increased risk of MACE after STEMI. Assessment of autoantibody levels paves the way for future therapies targeting specific molecular pathways associated with poor prognosis after an acute coronary event.

Frontiers in Cardiovascular MedicineVol. 12
University of Padua (IT), LUM Jean Monnet University (IT)
Openalex Percentile: Top 81%
Receptor Mechanisms and Signaling
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