A proposed model using glycation metrics and circulating biomarkers for the prevention of cardiovascular disease

Laboratory results of LDL, cTnI, A1c and fructosamine could be used sequentially to derive a cost-effective proxy for assessing <i>in situ</i> aging and deterioration of cardiovascular tissue. This model could theoretically predict the rate of cardiovascular aging by integrating four blood biomarkers into a dedicated algorithm guiding proactive diagnostics and treatment.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-08-12
DOI
https://doi.org/10.3389/fmed.2025.1624682
Primary Topic
Advanced Glycation End Products research
Type
article
Field-Weighted Citation Impact
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article

A proposed model using glycation metrics and circulating biomarkers for the prevention of cardiovascular disease

Timothy W. Valk, Carol McMorrow
Frontiers in Medicine
Advanced Glycation End Products research
article

A proposed model using glycation metrics and circulating biomarkers for the prevention of cardiovascular disease

Timothy W. Valk, Carol McMorrow
article en

Abstract

Laboratory results of LDL, cTnI, A1c and fructosamine could be used sequentially to derive a cost-effective proxy for assessing <i>in situ</i> aging and deterioration of cardiovascular tissue. This model could theoretically predict the rate of cardiovascular aging by integrating four blood biomarkers into a dedicated algorithm guiding proactive diagnostics and treatment.

Frontiers in MedicineVol. 12
Center for Independent Living (US)
Good health and well-being
Openalex Percentile: Top 76%
Advanced Glycation End Products research
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A proposed model using glycation metrics and circulating biomarkers for the prevention of cardiovascular disease — Timothy W. Valk, Carol McMorrow · Frontiers in Medicine (2025) | TGRS Research Map | TGRS